Epic 1 Week Itinerary in Italy: Visiting Rome, Florence, & Venice

Fit three of the most amazing cities in Italy into an epic one week itinerary for Italy. It’s the perfect Italian itinerary for first time visitors.

If you’re ready to explore the beauty of Italy, there’s no better way to start than with a whirlwind week-long adventure through the famous cities of Rome, Florence, and Venice. With over 10 visits to Italy under my belt, I can promise you – you’re in for a treat.

In just one week, you’ll experience the heart and soul of Italy – from the eternal city of Rome, to the art-filled streets of Florence, and finally, to the romantic canals of Venice. With each city offering a unique slice of Italian culture, you’re in for building memories you’ll daydream of for years to come.

What are we waiting for? Let’s take a look at how to plan your one week in Italy!

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Table of Contents

Day 1: Arrive in Rome

Start your trip to Italy by flying into one of the airports in Rome, Italy. Choose from Leonardo da Vinci International Airport in Fiumicino (FCO) or Giovan Battista Pastine International Airport in Ciampino (CIA).

Upon arriving in Rome, first check into your hotel. From there, you’ll start exploring the many wonders that Rome has to offer by strolling through the historic center. As Rome is huge, and even features a city-within-a-city with Vatican City right there, you’ll be spending 3 days here to scratch the surface of the city and its most famous attractions.

Now on to your exploration… The Spanish Steps are a fantastic starting point. This monumental staircase is not just beautiful but also a central hub to soak in the city’s atmosphere. From there, you can wander over to Piazza del Popolo. This expansive square features an ancient Egyptian obelisk and twin churches framing its entrance.

Next, make your way to the famous Trevi Fountain. This Baroque masterpiece is adorned with mythological figures and aquatic motifs. It is not only a sight to behold but also a place to participate in a famous tradition. Toss a coin over your left shoulder into the fountain to ensure your return to Rome one day. Admittedly, this little tradition has worked for me as I have returned to Rome multiple times!

After making your wish, find a cozy restaurant or trattoria nearby for a taste of authentic Roman cuisine, such as pasta carbonara or cacio e pepe.

Where to Stay in Rome

When it comes to finding the perfect place to stay in Rome, it’s all about location, location, location! If you want to be right in the heart of the action, the historic center, known as Centro Storico, is your go-to spot. It’s a bit pricier, but waking up with the Colosseum or the Spanish Steps on your doorstep is worth it.

For a more local vibe, try Trastevere. This charming and artsy neighborhood is home to cobblestone streets and a lot of nightlife. Or, if you’re looking to escape the hustle and bustle of the city, Aventine Hill offers a quieter locations with stunning views of the city.

No matter where you choose, Rome’s charm will be right at your doorstep. Plan to spend 3 nights in Rome before heading on to your next destination.

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Day 2: Rome

Today is all about exploring Rome’s ancient wonders – of which there are plenty! Begin with a visit to the iconic Colosseum. This grand amphitheater is where gladiators once fought to the death and other city spectacles took place during the Roman Empire. It’s an awe-inspiring structure and considered one of the 7 New Wonders of the World. To truly understand the Colosseum and its rich history, book a guided tour.

Pro Tip: Tickets and tours to the Colosseum do sell out. Make sure to book in advanc e!

Adjacent to the Colosseum, you’ll find the Roman Forum. This was considered the city center of ancient Rome. This archaeological site is filled with ruins of temples, basilicas, and government buildings, allowing you to step back in time and imagine daily life in ancient Rome.

Good news is your Colosseum tour typically includes entrance to the Roman Forum and Palantine Hill. From there, make sure to climb Palantine Hill too. It’s one of the seven hills of Rome and the legendary birthplace of the city. It gives you a great view of the Roman Forum.

After these famous sites, rest your feet and savor lunch at a local eatery nearby. Trust me, it’s a lot of walking! After lunch, take a walk to check out the impressive Baths of Caracalla. These once extravagant public baths date back to the 3rd century.

In the afternoon, make your way to another famous site, the Pantheon. This well-preserved Roman temple has been converted into a Christian church. Make sure to marvel at its enormous dome. Choose from entry with an audio guide or opt for a guided tour of the Pantheon.

Next up, Piazza Navona awaits. This lively square features Baroque fountains and is surrounded by cafes and shops. Here you can find an adorable place to have dinner. After all, it’s an ideal spot to relax and people-watch after your busy day checking out some of the most epic parts of Rome.

Day 3: Rome

Begin your third day in Rome with a visit to the Vatican City, home to St. Peter’s Basilica and the Vatican Museums. These iconic destinations house priceless art and religious treasures, including the Sistine Chapel. To avoid long lines, make sure to book tickets to the Vatican Museum and Sistine Chapel in advance.

Pro Tip: Tickets to the Vatican Museums and Sistine Chapel do sell out. Book in advance!

Whether you’re religious or not, don’t miss a tour of St. Peter’s Basilica. It’s an impressive experience with the large dome designed by Michelangelo really standing out. The interior is ornate with notable works like Bernini’s Baldachin and Michelangelo’s Pieta. Climbing to the top of the dome offers panoramic views of Vatican City and Rome.

For lunch, head to the popular neighborhood of Trastevere. It is known for its winding alleys and excellent restaurants. Enjoy a leisurely lunch savoring traditional Roman dishes.

In the afternoon, explore the Capitoline Hill, one of the most famous hills of ancient Rome. Here, you can visit the Capitoline Museums. They are home to a remarkable collection of ancient art and sculptures. Make sure not to miss the famous equestrian statue of Marcus Aurelius.

In the evening, enjoy a leisurely stroll along the banks of the Tiber River, where you can take in some picturesque views of the city.

This three-day introduction to Rome has taken you through its ancient ruins, iconic landmarks, and numerous neighborhoods. Each day offers a unique glimpse into the city’s rich history and culture. Stay tuned for the next part of your Italian adventure, where we’ll explore Florence!

Day 4: Rome to Florence

Today, you’ll leave Rome and take a high-speed train to Florence, the center of the Renaissance. After arriving and checking into your Florence hotel, your exploration of Florence begins.

How to Get from Rome to Florence

While there are many ways to get from Rome to Florence, jumping on the high-speed train is the best route! Trust me, I’ve tried it all, and this is the way to go. In just about 90 minutes, you’ll zip through the Italian countryside and arrive in the heart of Florence.

Best of all, you don’t have to face the hassle of airports. No security lines, no baggage claims – just pure, unadulterated travel joy. And, let’s not even think about renting a car and driving on the roads with the Italians.

For one, the tolls for driving in Italy seem to be never ending. For another, many insurances won’t cover you for driving in Italy due to their crazy drivers and road rules. We faced this very real challenge when we van-lifed through Italy!

What to See in Florence on Day 1

Upon arrival in Florence, check into your hotel and then start exploring with a visit to the breathtaking Florence Cathedral, locally known as the Duomo. This Gothic masterpiece is renowned for its striking red dome, designed by Brunelleschi, and Giotto’s Bell Tower. Climb to the top of the dome or the bell tower for breathtaking panoramic views of the city.

Pro Tip: This is another place that does sell out. Book ahead if you want to go inside the Duomo!

Next, venture to the Uffizi Gallery, one of the world’s greatest art museums. Inside, you’ll find an extensive collection of Renaissance and Baroque masterpieces. Here, you can admire works by Botticelli, Michelangelo, Leonardo da Vinci, and many others.

Pro Tip: The Uffizi Gallery features timed entry and is remarkably popular, so definitely book tickets ahead!

As evening approaches, savor a delightful dinner at a local Florentine restaurant. You’ll have the chance to indulge in Tuscan cuisine, such as hearty ribollita soup, tender Florentine steak, and delectable gelato for dessert.

Florence Duomo, Italy — The Duomo in Florence, Italy

Where to Stay in Florence

Finding a place to stay in Florence is all about enjoying the city’s Renaissance charm. The historic center, around the Duomo and Uffizi Gallery, is an ideal choice if you want to be within a gelato’s throw of iconic landmarks. It’s a busy area, so be prepared for that lively Florentine buzz.

For a quieter, artsy vibe, Oltrarno, on the other side of the Arno River, is perfect. You’ll find fewer crowds, quaint streets, and artisan workshops. Or, if you’re seeking a touch of luxury, the opulent Palazzo Pitti area is dotted with high-end hotels.

Whichever spot you pick, Florence’s timeless beauty will be at your doorstep. Perhaps best of all, Florence is easily walkable so if you stay in one of these neighborhoods, you don’t have to rely on public transit. Plan 2 nights in Florence to see the best of the city.

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Day 5: Florence

Your second day in Florence begins with a visit to the Accademia Gallery, home to Michelangelo’s iconic sculpture, David. Witness this famous masterpiece up close, and explore the museum’s other artworks and sculptures. It’s provides great insight into the artist’s genius.

Pro Tip: Book your Accademia Gallery tickets ahead. It too is a sell-out attraction!

After the Accademia Gallery, take your time to explore Florence’s historic center further. Piazza della Signoria, a square adorned with impressive sculptures and the imposing Palazzo Vecchio, await you.

Take a stroll across the famous Ponte Vecchio. This historic bridge is now lined with fairly gaudy jewelry shops. It leads you across the river to the Oltrarno neighborhood. Here you’ll find artisanal workshops and local cafes.

As the sun sets over Florence, consider enjoying a walk along the banks of the Arno River. It offers a romantic evening with amazing views of the city.

If you find you have more time to explore – or a day or two you can add to your one week Italian itinerary, add in more of the best things to do in Florence. There are plenty of churches, museums, and picturesque streets to explore. (Florence is one of my favorite Italian cities!)

Day 6: Florence to Venice

On day 6, you’ll bid farewell to Florence and board a high-speed train to Venice, where you’ll experience a whole different side of Italy. The train journey itself offers scenic views of the Italian countryside.

How to Get from Florence to Venice

Hopping on the high-speed train from Florence to Venice is by far the easiest way to get to Venice. In just a couple of hours, you’re transported from the Renaissance beauty of Florence to the enchanting canals of Venice.

The train is super comfortable, and you get to enjoy the Italian countryside as you zoom by. When you arrive at Venice’s Santa Lucia station, you’re practically right in the heart of the city. This makes it simple to get to your hotel in Venice.

What to See in Venice on Day 1

Upon your arrival in Venice, check-in to your hotel. Then head straight to St. Mark’s Square (Piazza San Marco). This central square is home to some of Venice’s most iconic landmarks, including St. Mark’s Basilica. It is an architectural masterpiece adorned with intricate mosaics and marbles.

Adjacent to the basilica, the Doge’s Palace showcases Venetian Gothic architecture. It was once the seat of government for the Venetian Republic. Both of these are “must sees” in Venice.

Pro Tip: Book your joint ticket in advance to save money and reserve your spot.

As evening falls, consider taking a romantic gondola ride along Venice’s meandering canals. It’s considered a quintessential experience that allows you to appreciate the city’s unique charm from the water. While you can book a small group tour in advance, you can also book individual rides on the spot. Just be prepared to pay as they can be fairly expensive!

Where to Stay in Venice

Venice is the city of canals and dreams! When it comes to finding your slice of Venetian heaven, location is key. Staying near the iconic St. Mark’s Square is fantastic for first-time visitors. You’ll be in the heart of the action, but do prepare for more tourists.

For a more local experience, districts like Dorsoduro or Cannaregio offer a quieter escape. Picture charming canals, hidden cafes, and a more relaxed pace. And if you’re up for a bit of splurge, booking a room overlooking the Grand Canal is worth every euro.

No matter where you decide to rest your head in Venice, this unique city has a lot to offer. Book 2 nights to round out your itinerary for a week in Italy.

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The Canals of Venice, Italy — The gondolas of Venice, Italy

Day 7: Venice

Your last day in Venice begins at the Rialto Bridge, the city’s most famous bridge. It is one of the few bridges that spans the Grand Canal. While you’re there, explore the lively Rialto Market. Here vendors sell fresh produce, seafood, and local specialties. It’s a great place to capture the essence of Venetian daily life.

Afterward, wander through the neighborhoods of Dorsoduro and Cannaregio. These offer picturesque streets, hidden squares, and local boutiques. In the heart of Dorsoduro, you’ll also find the Peggy Guggenheim Collection. This treasure trove of modern and contemporary art is displayed in the former home of the art patron.

As your days in Venice draw to a close, indulge in a waterside dinner at a Venetian restaurant. Enjoy the local seafood dishes and desserts that make up Venetian cuisine.

After dinner, enjoy an evening stroll through the canals to San Marco’s Square to enjoy the heart of Venice at night. It’s the perfect way to finish up your week in Italy.

San Marco's Square in Venice — San Marco’s Square in Venice, Italy

Day 8: Departure

Depending on your departure time, you may have some free time for last-minute shopping or additional sightseeing. Venice is known for its intricate Venetian glass, so consider picking up a unique souvenir to remember your trip.

As you make your way home, you’ll have time to reflect on your week in Italy that was filled with a busy schedule exploring Rome, Florence, and Venice. These cities are some of the most popular in Italy, but there are so many more places to visit, you’ll just have to travel back for a second trip!

Explore More of Italy

With this amazing 1 week itinerary of Florence, Rome, and Venice, you’re able to visit some of the best parts of Italy in 7 days. Of course, there are plenty of other amazing places to visit in Italy along with more to see in each of these Italian cities.

Learn more about visiting Italy with these helpful resources.

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Epic 1 Week Itinerary in Italy: Visiting Rome, Florence, & Venice